I love and translation the correlation of its level with clinical disease states [1 11 12,,]. Although no consensus on an optimal. Level of 25-hydroxyvitamin D has, been reached Vita - min D deficiency is defined by most experts as a level of less than 20 ng. Per millilitre (50 nmol per litre 13-16) [].A level of 25-hydroxyvitamin D of 21 to 29 ng per millilitre (52 to 72 nmol per litre) is considered as an insufficiency. Of, vitamin D and sufficient vitamin D should reach a level of 30 ng per millilitre or greater
[]. 17, In 1997The Institute of Medicine of the US National Academy of Sciences recommended new adequate intakes for vitamin D as 200 IU. For children and adults up to 50 years of age 400 IU, for adults 51 to 70 years, of age and 600 IU for adults 71 years of. Age or older
[]. However a 18, great number of studies revealed that without adequate, sun exposureChildren and adults require approximately 800 to 1000 IU per day [19-22].
Vitamin D intoxication is extremely rare. Studies. Showed that doses of more than 50 000 IU, per day which raises, 25-hydroxyvitamin D to more than 150 ng / ml is associated,, With hypercalcemia and hyperphosphatemia [8 9 23,,]. Even doses of 10 000 IU, of vitamin D3 per day for up to 5 months did. Not cause toxicity []. However 24,
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