2.4. Characterization of freeze-cas

2.4. Characterization of freeze-casted tabletsA digital microscopic system (VH-Z100, Keyence) was used torecord the overview of morphology of the pores and tablets. Thestructures of freeze-casted bodies were studied by using a scanningelectron microscope (Philips XL 30 ESEM). To get better SEMimages, samples for scanning microscopy examination weremounted and coated with platinum in a sputter coater beforeSEM measurement.The crushing strengths of produced tablets (£ 16 mm,h 10 mm) were measured with crushing force tester (TBH 30,Erweka), then the tensile strengths were calculated from thesedata and the geometrical parameters of tablets (Mitutoyo, Japan)via the equation of Fell and Newton (Fell and Newton, 1970).Porosities of tablets were determined by mercury porosimeterPascal 140 + 440 Series, Porotec. Dissolution profiles of tabletswere determined by a simple visible method. These methods werepresented in detail by Nguyen and Ulrich, 2014.The measurements of crushing force are reproduced six timesand all the other measurements were carried out in triplicate

2.4. Characterization of Freeze-casted tablets
A microscopic Digital System (VH-Z100, Keyence) was Used to
record The Overview of The Morphology of pores and tablets. The
Structures of Freeze-casted Bodies were studied by using a Scanning
Electron Microscope (Philips XL 30 ESEM). To Get Better SEM
images, samples for Scanning microscopy Examination were
Mounted and coated with Platinum in a sputter coater Before
SEM Measurement.
The Crushing strengths of produced tablets (£? 16 mm,
h? 10 mm) were measured with Crushing Force tester (TBH. 30,
Erweka), then The Tensile strengths were calculated from these
Data and The geometrical Parameters of tablets (Mitutoyo, Japan)
via The Equation of Fell and Newton (Fell and Newton, the 1,970th).
porosities of tablets were Determined by Mercury Porosimeter
Pascal 140. + 440 Series, Porotec. Dissolution profiles of tablets
were Determined by a Simple Method Visible. These methods were
Presented in detail by Nguyen and Ulrich, 2,014.
The measurements of Crushing Force are reproduced Six Times
and The Other measurements were carried out in all Triplicate.

2.4. Characterization of freeze-casted tablets
A digital microscopic system (VH-Z100 Keyence), was used to
record the overview. Of morphology of the pores and tablets. The
structures of freeze-casted bodies were studied by using a scanning
electron. Microscope (Philips XL 30 ESEM). To get better SEM
images samples for, scanning microscopy examination were
.Mounted and coated with platinum in a sputter coater before
SEM measurement.
The crushing strengths of produced tablets. (1 , 16 mm
H  10 mm) were measured with crushing force tester (TBH, 30
Erweka), then the tensile strengths were calculated. From these
data and the geometrical parameters of, tablets (Mitutoyo Japan)
via the equation of Fell and Newton (Fell and. Newton, the 1970).
.Porosities of tablets were determined by mercury porosimeter
Pascal 140, 440 Series Porotec. Dissolution profiles of. Tablets
were determined by a simple visible method. These methods were
presented in detail by Nguyen, and Ulrich 2014.
The. Measurements of crushing force are reproduced six times
and all the other measurements were carried out in triplicate.