According to this study of cationic surfactant niosomes as span20 with spermine-cationic and lipids are components that provide the best results for gene delivery, which may be born of cationic lipids sumptuous component that makes up the charge that there is niosome plus in a State so lysosyme acids result in membrane and endosomes destablize liberate DNA from the carriers into a cell, then the gene transcription and translation as such detergents Lysosomotropic lipophilic amine, which can cause a condition in the prachubuak acid in the lysosome, which will result in increasing the ability of endosomal escape of carrier (for Hughes and Liang, 1998). Thus, in the study should be performed sueng more education is the role of a cationic niosomes in Act engaged in gene delivery, m.d., and. Mechanism in the cell, as well as access to intracellular bawakan additional process transmitters.
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