These cytokines play many crucial r

These cytokines play many crucial roles in
H. pylori-associated gastritis through recruitment, activation, and infiltration of neutrophils into the sites of
infection as well as chronic inflammation and gastric
injury. Reactive oxygen and nitrogen species generated by activated inflammatory cells upon infection
can contribute to carcinogenesis through the formation
of DNA base lesions, such as 8-oxo-7,8-dihydro-20 -deoxyguanosine (8-oxodG), a marker of oxidative DNA
damage, resulting from G:C-to-T:A transversion. In
addition, 8-oxodG is remarkably increased in the gastric
epithelium of patients infected with H. pylori.

ผลลัพธ์ (แอฟริกา) 1:

Hierdie cytokines n rol speel in baie van kardinale belang.
H. pylori-verwante gastritis deur werwing, aktivering en infiltrasie van neutrofiele In Die terreine van.
infeksie asook chroniese inflammasie en maag.
Beserings. Reaktiewe suurstof en stikstof Spesies wat deur Geaktiveerde inflammatoriese selle op infeksie.
kan bydra tot die ontstaan ​​van kanker deur die vorming.
van DNA Base letsels, soos 8-oxo-7, 8 dihidro-20-deoxyguanosine (8-OxodG), 'n merker van oksidatiewe DNA.
skade, wat voortspruit uit G: C-om-te-T: 'n transversion. In
Daarbenewens 8-OxodG is merkwaardig vermeerder in die maag.
epiteel van pasiënte met H. pylori geïnfekteer is.