We investigated the antioxidant abi

We investigated the antioxidant ability, phenolic contents and cytotoxic effects of seven widely edible Nigerian medicinal plants, as a means of validating their ethnomedicinal use. Standard antioxidant assays assessed the capability of the extracts in scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (radical dotOH), and superoxide anion image radicals, as well as in inhibiting lipid peroxidation. The extracts possessed significant antioxidant activity compared to standards and the 7-amino actinomycin and WST-1 cytotoxicity assays proved that they were non-toxic to human peripheral blood mononuclear cells, and the A2.01 cell line. Landolphia owariensis and Irvingia gabonensis had the most antioxidant activity in the DPPH assay, compared to ascorbic acid. They also significantly inhibited lipid peroxidation. I. gabonensis and Nauclea latifolia powerfully quenched the radical dotOH radical compared to α-tocopherol. The extracts' antioxidant activity and lipid peroxidation inhibitory potencies correlated with their phenolic and flavonoid contents. Thus, the antioxidant activities could be factors contributing substantially to their traditional medicinal use.

We investigated the antioxidant ability, phenolic contents and cytotoxic effects of seven widely edible Nigerian medicinal plants, as a means of validating their ethnomedicinal use. Standard antioxidant assays assessed the capability of the extracts in scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (radical dotOH), and superoxide anion image radicals, as well as in inhibiting lipid peroxidation. The extracts possessed significant antioxidant activity compared to standards and the 7-amino actinomycin and WST-1 cytotoxicity assays proved that they were non-toxic to human peripheral blood mononuclear cells, and the A2.01 cell line. Landolphia owariensis and Irvingia gabonensis had the most antioxidant activity in the DPPH assay, compared to ascorbic acid. They also significantly inhibited lipid peroxidation. I. gabonensis and Nauclea latifolia powerfully quenched the radical dotOH radical compared to α-tocopherol. The extracts' antioxidant activity and lipid peroxidation inhibitory potencies correlated with their phenolic and flavonoid contents. Thus, the antioxidant activities could be factors contributing substantially to their traditional medicinal use.

We investigated the antioxidant ability phenolic contents, and cytotoxic effects of seven widely edible Nigerian medicinal. Plants as a, means of validating their Ethnomedicinal use. Standard antioxidant assays assessed the capability of the extracts. In, scavenging 2 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (radical dotOH), and superoxide anion image radicals as well,, As in inhibiting lipid peroxidation. The extracts possessed significant antioxidant activity compared to standards and the. 7-amino actinomycin and WST-1 cytotoxicity assays proved that they were non-toxic to human peripheral blood mononuclear. Cells and the, A2.01 cell line. Landolphia owariensis and Irvingia gabonensis had the most antioxidant activity in the DPPH. Assay compared to, ascorbic acid. They also significantly inhibited lipid peroxidation. I. Gabonensis and Nauclea latifolia. Powerfully quenched the radical dotOH radical compared to α - tocopherol. The extracts' antioxidant activity and lipid peroxidation. Inhibitory potencies correlated with their phenolic and flavonoid contents. Thus the antioxidant, activities could be factors. Contributing substantially to their traditional medicinal use.