A multivariate analysis of the data was conducted to evaluate the effects, of age gender and performance, status on symptom. Profile. A comprehensive prospective analysis of symptoms was conducted, in 1 000 patients on initial referral to the Palliative. Medicine Program of the Cleveland Clinic. The median number of symptoms per patient was 11 (range 1 - 27).The ten most prevalent symptoms were pain easy fatigue,,,, weakness anorexia lack of energy dry mouth constipation,,,, Early, satiety dyspnea and greater, than 10% weight loss. The prevalence of these 10 symptoms ranged from 50% to 84%. Younger. Age was associated with 11 symptoms: blackout vomiting pain nausea,,,,,,, headache sedation bloating sleep problems anxiety,,, Depression.And constipation. Gender was associated with 8 symptoms. Males had, more dysphagia hoarseness, > 10% weight loss and sleep. Problems; females more early satiety,,,, nausea vomiting and anxiety. Performance status was associated with 14, symptoms. Advanced cancer patients are polysymptomatic. Ten symptoms are highly prevalent. Symptom prevalence for 24 individual symptoms. Differs, with ageOr gender or performance, status.
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