The phenomenon known as "matrix-induced enhancement effect." is not only observed in the analysis of pesticides, in food. But also in Chinese herbs. Several approaches have been proposed to overcome the, matrix-induced effect but each method. Has serious limitations. Compared with standard calibration methods the procedure, with adding analyte protectants offers. A more convenient and effective route to solve the problem. In the, current study we have analyzed 195 types of pesticides. In Chinese herbs by gas chromatography - mass spectrometry (GC - MS), and the compounds that are susceptible to matrix effect. Were picked up and confirmed. In addition several analyte, protectants were evaluated and the most effective combination. Was determined. D-Ribonic acid - γ - lactone (2 mg / ml) and D-sorbitol (1 mg / ml) were shown to be the best analyte protectants. For the analysis of most pesticides.
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