Four, new compounds citrusosides A-D (1-4), and 15 known compounds were isolated from the Hexanes and CH2Cl2
extracts of. The peels of Citrus hystrix fruits. Compound 1 is a 1-O-isopropyl-6-O - - D-glucopyranosyl ester of 5 '', 9 '' -
Dimethyl-2 '', '', 8 - decadienoic Acid. Compounds 2-4 possess a 1-O-isopropyl - - D-glucopyranosyl and a dihydroxyprenylfuranocoumarin
.Moiety conjugated to the 3-hydroxy-3-methylglutaric acid as diesters. Several furanocoumarins were
evaluated for their. Cholinesterase inhibitory activity. (R) - () - 6 '- Hydroxy-7' - methoxybergamottin, (R) - () - 6 ', 7' -
dihydroxybergamottin and (,, ) - isoimparatorin showed IC50 values of 11.2 (0.1 15.4 (,, 0.3 and 23 (0.2, thermal M
respectively.Bioassay results indicated that the presence of a dioxygenated geranyl chain in the test compounds is
crucial for the inhibitory. Activity.
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