There is a reason of temperance, as well as the need to have the immune system in some. To affect any changes caused by both external and internal. must rely on knowledge prudence.
Moderation, reasonableness, including the need to have a reasonably good immune system. The impact of any Arising from changes in the external and must rely on the knowledge of prudence.
Moderation, rationality and necessity to immune system in good enough to มควร on the impact of any resulting from changes both inside and outside. This will require knowledge, prudence.