The first effects from the surgery, considered as the fundamental issue is to cause disease by surgery because it is an action that affects directly to our body and is disrupting the body may cause subsequent effects.
The first effect of surgery that is the fundamental problem is caused by the disease. Because the surgery is an act that directly effect our body. And a disturbing body Potentially affected by it.
The effect of surgery is the first fundamental problem is to cause disease. Due to the surgical actions that directly affect the body and a disturbed body. May cause impact.