The IC50 of a drug can be determine

The IC50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist on reversing agonist activity. IC50 values can be calculated for a given antagonist by determining the concentration needed to inhibit half of the maximum biological response of the agonist.

ผลลัพธ์ (เวลส์) 1:

Gall y IC50 o gyffur cael ei benderfynu gan adeiladu gromlin dos-ymateb ac yn archwilio effaith gwahanol grynodiadau o wrthwynebydd ar wrthdroi weithgaredd agonist. Gellir gwerthoedd IC50 cael eu cyfrifo ar gyfer wrthwynebydd a roddwyd gan benderfynu ar y crynodiad sydd eu hangen i atal hanner yr ymateb biolegol uchafswm y agonist.