Carbofuran is a broad spectrum carb

Carbofuran is a broad spectrum carbamate insecticide which inhibits cholinesterase. In the recent past
several carbofuran related homicide and suicide cases were reported in Sri Lanka. The concentration of
carbofuran found in blood, bile and/or tissues in eight fatal cases were presented in this paper. Liquid–
liquid extraction with chloroform was carried out with tissue and beverage samples while blood and bile
samples were roller mixed with n-hexane and finally extracted into acetonitrile. Qualitative analysis of
carbofuran in biological specimens was carried out using TLC and GC–MS. Presence of carbofuran and its
metabolite carbofuran phenol were confirmed by GC–MS. The quantitative analysis was carried out
using a validated method where Zorbax Eclips XDB C18 column was used in HPLC with photo diode array
detector and GC–MS. In blood, bile, liver and stomach contents/stomach and contents both carbofuran
and carbofuran phenol were identified, while in certain cases only the metabolite, carbofuran phenol
was identified in blood. The carbofuran levels ranged from 0.4 to 18 mg/ml in blood, 0.4 to 60 mg/ml in
bile, 2.2 mg/g in liver and 0.3 to 300 mg/g in stomach contents/stomach and contents

ผลลัพธ์ (อังกฤษ) 2:

Carbofuran is a broad spectrum carbamate insecticide which inhibits cholinesterase. In the recent Past
several carbofuran and related homicide Suicide Cases were reported in Sri Lanka. The concentration of
carbofuran Found in Blood, bile and / or tissues in Eight Fatal Cases were Presented in this Paper. Liquid-
Liquid extraction with chloroform was carried out with tissue samples and beverage while Blood and bile
samples were mixed with n-hexane Roller and finally extracted Into acetonitrile. Analysis of qualitative
carbofuran in Biological specimens was carried out using TLC and GC-MS. Presence of carbofuran and its
metabolite carbofuran phenol were confirmed by GC-MS. Analysis was carried out the quantitative
method using a Validated where Eclips Zorbax XDB C18 column was used in HPLC with diode array Photo
Detector and GC-MS. In Blood, bile, liver and stomach contents / stomach contents and both carbofuran
and carbofuran phenol were identified, while in certain Cases only the metabolite, carbofuran phenol
was identified in Blood. The carbofuran levels ranged from 0.4 to 18 mg / ml in Blood, 0.4 to 60 mg / ml in
bile, 2.2 mg / 0.3 G in liver and to 300 mg / G in stomach contents / stomach and contents.