Introduction
How nanometer-scale molecular components construct
micron-scale cells of specific shapes and sizes remains an
outstanding question in biology. How are cell shapes generated?
Are there reasons why cells have adopted certain
shapes over others? Although many shape-determining factors
have been identified across divergent organisms, mere
characterization of individual cellular components has not
revealed how shape is determined, nor has it provided much
insight into the context under which these shapes evolved.
Addressing these questions will require the integration of
biology, physics, and chemistry. For instance, in addition to
traditional molecular cell biology, it will be important to
understand the role of cellular mechanics, the material
properties of cells, their microenvironment, and evolutionary
constraints. Comparisons among organisms with a common
shape may help to reveal general principles that dictate
shape determination and its evolutionary origins.
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Inleiding
Hoe nanometer-skaal Konstrueer molekulêre komponente
van selle Micron-skaal Spesifieke vorms en groottes Bly 'n
Uitstaande vraag in biologie. Hoe word Cell Vorms Generated?
Is daar redes waarom het aangeneem Sekere selle
Vorms oor ander? Hoewel baie Shape-bepalende faktore
is geïdentifiseer Across uiteenlopende organismes, Mere
karakterisering van Individuele Cellular komponente nie
onthul hoe Shape bepaal word, of het dit 'n groot mate
insig in die konteks waaronder hierdie vorms ontwikkel het.
Die aanspreek van hierdie vrae sal vereis die integrasie van.
biologie, fisika, chemie. Byvoorbeeld, in toevoeging tot
Tradisionele molekulêre Selbiologie, sal dit belangrik wees om
die rol van Cellular Meganika verstaan, die materiaal
Properties selle, hul mikro, en Evolusionêre
beperkings. Tussen organismes vergelykings met 'n gemeenskaplike
Shape Mag Help algemene beginsels wat dikteer te openbaar
Shape vasberadenheid en SY evolusionêre oorspronge.
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