Even established antifungals, such

Even established antifungals, such as azoles, can specifically
inhibit hyphal growth. In our laboratory, we examined the
effects of low levels of azoles on the ability of C. albicans to
adhere, invade and damage vaginal epithelial cells. These low
levels of azoles did not influence yeast growth, but effectively
inhibited extensive hyphal elongation [84]. Interestingly,
although adhesion to and invasion of vaginal epithelial cells
were not affected, the damage caused to these cells was greatly
reduced upon azole treatment, and this was most likely due to
reduced hyphae formation. These data provide evidence that low
levels of azoles influence specific activities of C. albicans during
distinct stages of epithelial infections and provide a proof of
principle that inhibition of hypha formation can be used as a
therapeutic option

ผลลัพธ์ (อังกฤษ) 2:

Even established antifungals, such as Azoles, Can specifically
inhibit hyphal growth. In our Laboratory, we examined the
effects of low levels of Azoles on the ability of C. albicans to
Adhere, vaginal epithelial cells Invade and damage. These low
levels of Azoles did not influence yeast growth, but effectively
inhibited Extensive hyphal elongation [84]. Interestingly,
Although vaginal epithelial cells adhesion to and Invasion of
AFFECTED were not, the damage caused to these cells was greatly
reduced upon azole Treatment, and this was Most likely Due to
reduced hyphae Formation. These Data Evidence that provide low
levels of C. albicans during Azoles influence of specific Activities
Distinct stages of epithelial infections and provide a Proof of
principle that inhibition of hypha Formation Can be used as a
therapeutic Option.

ผลลัพธ์ (อังกฤษ) 3:

Even established antifungals such as azoles can specifically,,,Inhibit hyphal growth. In, our laboratory we examined the.Effects of low levels of azoles on the ability of C. Albicans to.Adhere invade and, damage vaginal epithelial cells. These low.Levels of azoles did not influence yeast growth but effectively,,Inhibited extensive hyphal elongation []. Interestingly 84,Although adhesion to and invasion of vaginal epithelial cells.Were not affected the damage, caused to these cells was greatly.Reduced upon, azole treatment and this was most likely due to.Reduced hyphae formation. These data provide evidence that low.Levels of azoles influence specific activities of C. Albicans during.Distinct stages of epithelial infections and provide a proof of.Principle that inhibition of hypha formation can be used as a.Therapeutic option.