While PNMT methylates norepinephrin

While PNMT methylates norepinephrine into the active compound epinephrine, norepinephrine can also be methylated by catechol-O-methyl transferase (COMT), another methyltransferase which adds a methyl group in a different location, in turn producing the inactive compound metanephrine. Methyltransferases are very common in the catecholamine synthesis and deactivation pathways.[7]
PNMT is also involved in the biosynthesis of N-methylated trace amines: it metabolizes phenethylamine into N-methylphenethylamine (a positional isomer of amphetamine), p-octopamine into synephrine, and p-tyramine into N-methyltyramine.[

ผลลัพธ์ (อังกฤษ) 2:

While PNMT methylates norepinephrine into the active compound epinephrine, norepinephrine can also be methylated by catechol-O-methyl transferase (COMT), another methyltransferase which adds a methyl group in a different location, in turn producing the inactive compound metanephrine. Methyltransferases are very common in the catecholamine synthesis and deactivation pathways. [7]
PNMT is also involved in the biosynthesis of N-methylated Trace amines: it metabolizes phenethylamine Into N-Methylphenethylamine (a positional isomer of amphetamine), P-putative octopamine Into synephrine,. and p-tyramine into N-methyltyramine. [.