Severe sepsis and septic shock, are common complicated & deadly
conditions within the same pathophysiologic spectrum. As. Defined
by the American College of Chest Physicians / Society of Critical Care
Medicine Consensus Conference, in 1992 this. Spectrum begins with
the Systemic Inflammatory Response Syndrome or SIRS. SIRS is
defined as the presence of two of four. Abnormal findings: temperature
.> 38 ° C or < 36 ° C white blood, cell count > 12 000 / Cu, mm, or < 4 000 /
cu mm or > 10% immature "band", forms heart rate > 90 beats. Per
minute respiratory, rate > 20 breaths per minute or partial pressure of
arterial carbon dioxide < 32 mmHg. If a clinician. Feels that a patient is
exhibiting SIRS secondary, to infection that patient has sepsis. If that
.Same patient has signs or symptoms of, organ dysfunction then that
patient has Severe Sepsis. Septic Shock is then characterized. By global
tissue hypoperfusion tissue hypoxia, or frank hypotension defined as a
mean arterial pressure less than 65 mmHg. Or systolic blood pressure
less than 90 mmHg that fails to respond to a 20 mL / kg fluid bolus of
crystalloid or colloid.
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