ฉันรักแปลภาษา1. IntroductionThe Cur

ฉันรักแปลภาษา1. Introduction
The Curcuma genus (family Zingiberaceae) contains approximately 50 species found in Southeast Asia. Curcuma xanthorrhiza Roxb., commonly known as temu lawak or Javanese turmeric in Indonesia, is a well-known traditional medicinal plant with its anti-inflammatory ( Ozaki, 1990) and anticancer (Park et al., 2008) activities as well as protective effects against liver damage (Lin et al., 1995). Terpenoids and curcuminoids were reported as its most abundant compounds ( Uehara et al., 1992 and Sukari et al., 2008). As part of our studies on C. xanthorrhiza, some novel sesquiterpenoids were reported ( Zhang et al., 2014), and some of the sesquiterpenoids from C. xanthorrhiza showed acetylcholinesterase (AChE) inhibitory acitivities ( Zhang et al., 2013). AChE inhibitors are important medications that have passed FDA approval for the treatment of mild to moderate Alzheimer's disease (Lau and Brodney, 2008). The AChE inhibitory activities of sesquiterpenoids indicated the potential of C. xanthorrhiza in the therapy of Alzheimer's disease. Discovering effective and safe AChE inhibitors from traditional medicines is an important way to prevent and treat Alzheimer's disease.

Further bioassay-guided investigation on C. xanthorrhiza led to the isolation of nine compounds for the first time, including one new Guaiane-type sesquiterpenoid 1, four of which showed AChE inhibitory activities. To further explore the potential of C. xanthorrhiza against Alzheimer's disease, the SIRT1 (silent information regulator two homologue 1) promotion activities of the compounds were tested using HEK293 cell lines. SIRT1 is a member of the sirtuin family that possesses NAD+-dependent deacetylase activity and regulates a variety of cellular processes such as energy metabolism, cell-cycle progression and aging (Raghavan and Shah, 2012). SIRT1 is becoming an important drug target for new therapies in the treatment of neurodegenerative diseases ( Huber and Superti-Furga, 2011, Braidy et al., 2012 and Min et al., 2013). Small molecule SIRT1 activators or compounds that promote its expression could be candidates for the treatment of aging and age-related diseases ( Bonda et al., 2011, Karagiannis and Ververis, 2012 and Hubbard and Sinclair, 2014).

ผลลัพธ์ (อังกฤษ) 2:

I love translating one language. Introduction
The Curcuma genus (Family Zingiberaceae) contains approximately 50 species Found in Southeast Asia. Curcuma xanthorrhiza Roxb., Commonly Known as temu Lawak or Javanese Turmeric in Indonesia, is a well-Known Traditional Medicinal Plant with ITS Anti-inflammatory (Ozaki, 1,990. ) and anticancer (Park et al., 2008) activities as well as protective effects against liver damage (Lin et al., 1995). Terpenoids and curcuminoids were reported as its most abundant compounds (Uehara et al., 1992 and Sukari et al. ., 2008). As part of our studies on C. xanthorrhiza, some novel sesquiterpenoids were reported (Zhang et al., 2014), and some of the sesquiterpenoids from C. xanthorrhiza showed acetylcholinesterase (AChE) inhibitory acitivities (Zhang et al. , 2013). AChE inhibitors are important medications that have passed FDA approval for the treatment of mild to moderate Alzheimer's disease (Lau and Brodney, 2008). The AChE inhibitory activities of sesquiterpenoids indicated the potential of C. xanthorrhiza in the therapy of Alzheimer's disease. . Discovering effective and Safe AChE inhibitors from Traditional Medicines is an important Way to Prevent and Treat Alzheimer's disease.

Further bioassay-Guided Investigation on C. xanthorrhiza LED to the isolation of Nine compounds for the First time, including one New Guaiane-Type Sesquiterpenoid 1. , four of which showed AChE inhibitory activities. To further explore the potential of C. xanthorrhiza against Alzheimer's disease, the SIRT1 (silent information regulator two homologue 1) promotion activities of the compounds were tested using HEK293 cell lines. SIRT1 is a member of the. sirtuin family that possesses NAD + -dependent deacetylase activity and regulates a variety of cellular processes such as energy metabolism, cell-cycle progression and aging (Raghavan and Shah, 2012). SIRT1 is becoming an important drug target for new therapies in the treatment of neurodegenerative. diseases (Huber and Superti-Furga, 2011, Braidy et al., 2012 and Min et al., 2013). Small molecule SIRT1 activators or compounds that promote its expression could be candidates for the treatment of aging and age-related diseases (Bonda. et al., 2011, Karagiannis and Ververis, 2012 and Hubbard and Sinclair, 2014).

ผลลัพธ์ (อังกฤษ) 3:

I love 1, Introduction translation.The Curcuma genus (family Zingiberaceae) contains approximately 50 species found in Southeast Asia. Curcuma xanthorrhiza. Roxb, commonly known as Temu lawak or Javanese turmeric in Indonesia is a, well-known traditional medicinal plant with. Its anti-inflammatory (Ozaki 1990), and anticancer (Park et al, 2008) activities as well as protective effects against. Liver damage (Lin et al, 1995). Terpenoids and curcuminoids were reported as its most abundant compounds (Uehara et al, 1992 and. Sukari et al, 2008). As part of our studies on C. Xanthorrhiza some novel, sesquiterpenoids were reported (Zhang et al.,. 2014), and some of the sesquiterpenoids from C. Xanthorrhiza showed acetylcholinesterase (AChE) inhibitory acitivities. Zhang et al, 2013). AChE inhibitors are important medications that have passed FDA approval for the treatment of mild to. Moderate Alzheimer "s disease (Lau, and Brodney 2008). The AChE inhibitory activities of sesquiterpenoids indicated the potential. Of C. Xanthorrhiza in the therapy of Alzheimer "s disease. Discovering effective and safe AChE inhibitors from traditional. Medicines is an important way to prevent and treat Alzheimer "s disease.Further bioassay-guided investigation on C. Xanthorrhiza led to the isolation of nine compounds for the, first time including. One new Guaiane-type sesquiterpenoid 1 four of, which showed AChE inhibitory activities. To further explore the potential. Of C. Xanthorrhiza against Alzheimer ", s disease the SIRT1 (silent information regulator two homologue 1) promotion activities. Of the compounds were tested using HEK293 cell lines. SIRT1 is a member of the sirtuin family that possesses NAD+-dependent. Deacetylase activity and regulates a variety of cellular processes such as, energy metabolism cell-cycle progression and. Aging (Raghavan, and Shah 2012). SIRT1 is becoming an important drug target for new therapies in the treatment of neurodegenerative. Diseases (Huber, and Superti-Furga 2011 Braidy et, Al, 2012 and Min et al, 2013). Small molecule SIRT1 activators or. Compounds that promote its expression could be candidates for the treatment of aging and age-related diseases (Bonda et. Al, 2011 Karagiannis and, Ververis 2012 and, Hubbard, and Sinclair 2014).