ABSTRACTObjectives: To determine if

ABSTRACT
Objectives: To determine if chronic pulmonary
diseases adversely impact selected outcomes in
hospitalised patients who have various allergic
conditions including anaphylaxis.
Design: A population-based cohort study.
Participants: A statewide hospital inpatient discharge
database from Texas, USA, covering the years 2004–
2007 was analysed. Patients with anaphylaxis and
other allergic conditions were identified using the
International Classification of Diseases, Ninth Revision,
Clinical Modification codes. Within each group of
patients (the overall group with various selected
allergic conditions and the subgroup with anaphylaxis),
the exposure variables were 11 chronic pulmonary
diseases including asthma, chronic obstructive
pulmonary disease (COPD) and cystic fibrosis.
Primary outcome measures: Admission to an
intensive care unit, a prolonged (>3 days) hospital stay,
receipt of mechanical ventilation and death in hospital.
Logistic regression was used to calculate adjusted OR
and 95% CI for these four outcomes.
Results: 30 390 patients with allergic conditions were
identified, of whom 2410 had anaphylaxis. The
following results pertain to the subcohort of patients
with anaphylaxis. Median age was 50 years
(range 0–95 years) and 1470 (61%) were female. The
hospital mortality was 2.7%. Although asthma was not
associated with hospital mortality (OR=1.27, 95% CI
0.55 to 2.90), asthmatics had more than twice the odds
of non-asthmatics of receiving mechanical ventilation
(OR=2.45, 95% CI 1.81 to 3.33). Chronic bronchitis,
COPD, emphysema and interstitial lung diseases (ILDs)
were also associated with an increased risk of requiring
mechanical ventilation. Chronic bronchitis and COPD
were associated with a prolonged length of stay:
OR=2.69 (95% CI 1.45 to 4.98) and OR=1.86 (95%
CI 1.30 to 2.66), respectively. ILD was the only chronic
pulmonary disease associated with an elevated risk of
hospital mortality: OR=8.71 (95% CI 1.48 to 51.20).
Conclusions: In this unique analysis of a large
database, we found that asthma, COPD and other chronic
pulmonary diseases increased the risk of adverse
outcomes among hospitalised patients with anaphylaxis.

ผลลัพธ์ (อังกฤษ) 2:

ABSTRACT
Objectives: To Determine IF chronic pulmonary.
Diseases adversely Impact Selected outcomes in
hospitalized patients Who Have Various allergic
conditions including anaphylaxis.
Design: A Population-based cohort Study.
Participants: A Statewide Hospital Inpatient discharge.
Database from Texas, USA, COVERING The years 2004th. -
the 2007th was analyzed. Patients with anaphylaxis and
allergic conditions were identified using The Other.
International Classification of Diseases, Ninth Revision,.
Clinical Modification Codes. Within Each Group of
patients (The Overall Group with Various Selected.
allergic conditions and The subgroup with anaphylaxis),.
The Exposure variables were 11 chronic pulmonary.
Diseases including asthma, chronic obstructive
pulmonary disease (COPD) and cystic fibrosis.
Primary outcome Measures: Admission to an.
intensive Care Unit, a prolonged (> 3 days) Hospital Stay,.
Receipt of mechanical Ventilation and Death in Hospital.
Logistic regression was Used to Calculate adjusted OR.
and 95% CI for these Four outcomes.
Results: 30 390 patients with allergic conditions were.
identified , of whom 2410 had anaphylaxis. The
following results Pertain to The Subcohort of patients.
with anaphylaxis. Median Age was 50 years
(Range 0-95 years) and 1,470th (61%) were female. The
Hospital mortality was 2.7%. Although asthma was Not
Associated with Hospital mortality (OR = 27/1, 95% CI.
.55 to 2.90), asthmatics had more than Twice The Odds.
of non-asthmatics of receiving mechanical Ventilation.
(OR = two forty-five, 95% CI 1.81 to 3.33). Chronic bronchitis,
COPD, emphysema and interstitial Lung Diseases (ILDs).
were also Associated with an increased risk of requiring.
mechanical Ventilation. Chronic bronchitis and COPD
were Associated with a prolonged Length of Stay:.
OR = 2.69 (95% CI one forty-five to 4.98) and OR = 1.86 (95%.
CI 30.01 to 2.66), respectively. ILD was The only chronic
pulmonary disease Associated with an elevated risk of.
Hospital mortality: OR = 8.71 (95% CI 1.48 to 51.20).
Conclusions: In this Unique analysis of a Large.
Database, We Found that asthma, COPD and Other chronic.
pulmonary Diseases The increased risk of adverse
outcomes Among hospitalized patients with anaphylaxis.