In traditional ionic liquids (ILs)-

In traditional ionic liquids (ILs)-based microextraction, ILs are often used as extraction and dispersive
solvents; however, their functional effects are not fully utilized. Herein, we developed a novel ionic liquid
1-butyl-3-methylimidazolium naphthoic acid salt ([C4MIM][NPA]) with strong acidity. It was used as a
mixed dispersive solvent with conventional [C2MIM][BF4] in ‘‘functionalized ionic liquid-based nonorganic
solvent microextraction (FIL-NOSM)” for determination of tetracycline antibiotics (TCs) in milk
and eggs. Utilization of [C4MIM][NPA] in FIL-NOSM method increased extraction recoveries (ERs) of
TCs by more than 20% and eliminated the pH adjustment step because of its strong acidity. Under
optimized conditions based on central composite design, the ERs of four TCs were 94.1–102.1%, and
the limits of detection were 0.08–1.12 lg kg
1 in milk and egg samples. This proposed method provides
high extraction efficiency, less pretreatment time and requires non-organic solvents for determination of
trace TC concentrations in complex animal-based food matrices

ผลลัพธ์ (อังกฤษ) 2:

Ionic liquids in Traditional (ILs) microextraction-based, ILs are often used as extraction and dispersive
solvents; however, their functional effects are not fully utilized. Herein, we developed a novel Ionic Liquid
1-butyl-3-methylimidazolium Naphthoic Salt acid ([C4MIM] [NPA]) with strong acidity. It was used as a
dispersive Solvent mixed with conventional [C2MIM] [BF4] in '' functionalized Ionic Liquid-based nonorganic
Solvent microextraction (FIL-NOSM) "for determination of tetracycline antibiotics (TCs) in Milk
and Eggs. Utilization of [C4MIM] [NPA] in FIL-NOSM method Increased extraction recoveries (ERs) of
TCs by more than 20% and eliminated the Step pH adjustment because of strong ITS acidity. Under
conditions based on Optimized Design Central composite, the ERs of Four TCs were 94.1-102.1%, and
the limits of Detection were 12:08 a.m. to 1:12 lg kg? 1 in Egg and Milk samples. Proposed this method provides
High extraction efficiency, Less pretreatment time and requires non-Organic solvents for determination of
TC Trace concentrations in Complex Food Animal-based matrices.