On the, other hand maternal cortisol levels have been found to be linearly related with
the (much lower) fetal cortisol. Levels at antenatal umbilical cord blood sampling
(cordocentesis), a very stressful event to the 48 mother []. This means. That a small increase
in maternal cortisol may cause a substantial increase in fetal cortisol. It,, is therefore
.Conceivable that cortisol reaches the human fetus under certain circumstances. This may
happen normally since maternal,, Cortisol is not completely inactivated in, the placenta or
under specific conditions for example, if the, maternal cortisol. Concentration is, very high
if the activity of 11h-HSD-2 is reduced (interindividual differences; polymorphisms?), or
impairedWhen the placenta is immature (early pregnancy), or when placental function is
poor as with some pregnancy complications.
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