Education dried root extract trigonostemon. Finding a suitable solvent. Inhibition of tyrosinase enzyme extract. And formulated skin cream. The separation plant are two types of male trigonostemon. And female trigonostemon Extraction with solvents two types of water and ethanol, 95% were found trigonostemon male and female extracted with water, the percentage of yield (% yield) of 5.3436 and 5.4209 respectively and trigonostemon males and females. extracted with ethanol 95% and the percentage of yield (% yield) of 1.4480 and 1.7145 respectively, compare the dissolution of the extract. In organic solvents showed that the water extract. Found that water is the best solvent. Extract, extracted with ethanol, 95% ethanol, 95% found solvents, cosmetics and found that propylene glycol as a solvent at best. Inhibition of enzyme tyrosinase by way Dopachrome method reported in the study is the concentration of the extract crude displayed inhibit 50% (IC50) found that extracts of trigonostemon male and female extracted. Water with IC50 values of 0.5036 μg / ml and 0.5169 μg / ml, respectively, and extract trigonostemon male and female extracted with ethanol, with IC50 values of 4.8200 μg / ml and 1.8320 μg / ml, respectively, for the veto. The enzyme tyrosinase inhibitory substances extracted very good. When comparing the effect of inhibiting the enzyme tyrosinase extract of Aloe Noda's Red Bull extracted with water. Kojic acid is able to better estimate and 2.9 times more potent Alpha-Arbtin approximately 3.2-fold extract Lo Wada holding red female extracted with water. Effective better Koic acid approximately 2.8 times and a better activity than Alpha-Arbtin about 3.1 times the extract trigonostemon male and female extracted with ethanol is inhibitory inferior Kojic acid and Alpha arbutin be developed. Complexion Cream Recipes Skin cream products that are white. PH - alkalinity (pH) of 5.00 with the viscosity 95 260 Sentinel Point of stability testing under accelerated by centrifugation (Centrifuge) found that color, aroma and acidity - alkalinity (. pH) does not change No precipitation And no separation between fat and water. Suitable for further development as cosmeceuticals.
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