Essential oil of Bergamot (BO) was

Essential oil of Bergamot (BO) was investigated for anti-inflammatory activity using
carrageenan-induced rat paw oedema test.
Methods: For the anti-inflammatory activity measurement six different groups were established
and BO was administered in three different doses: 0.025, 0.05 and 0.10 mL/kg. Indomethacin was
used as a reference agent.
Results: It was found that reduction in the inflammation was 95.70% with indomethacin,
27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO.
Indomethacin showed the strongest anti-inflammatory activity among the drugs used. The
strongest anti-inflammatory activity of BO was seen with 0.10 mL/kg dosage. Median effective
dose (ED50) value of BO was found to be 0.079 mL/kg.
Conclusion: The results showed that BO posseses promising anti-inflammatory effect.
Key words: Citrus aurantium subsp. bergamia, Bergamot oil, anti-inflammatory activity,
carrageenan-oedema. It has been reported that bergamot oil
exhibited antifungal activity against some
dermatophytes and antibacterial activity
against Campylobacter jejuni, Escherichia
coli O157, Listeria monocytogenes, Bacillus
cereus and Staphylococcus aureus (9,10).
Some of the components of BO, limonene,
linalool, linalyl acetate and alpha-pinene,
were shown to have anti-inflammatory effects
(11-13). Therefore it is likely that BO has
anti-inflammatory activity.
In this study, essential oil extract of
Bergamot oil was investigated for its antiinflammatory
activity using carrageenaninduced
rat paw oedema test

ผลลัพธ์ (อังกฤษ) 2:

Essential Oil of Bergamot (BO) was investigated for Anti-inflammatory Activity using.
carrageenan-induced Rat Paw edema Test.
Methods: For The Anti-inflammatory Activity Measurement Six different groups were established.
and BO was Administered in Three different doses: 0.025, 12:05 a.m. and. 0.10 mL / kg. Indomethacin was
used as A Reference Agent.
Results: It was Found that Reduction in The inflammation was 95.70% with indomethacin,.
27.56% with 0.025 mL / KG BO, 30.77% with 0:05 mL / KG BO and 63.39% with 0.10 mL / KG BO. .
Indomethacin showed The Strongest Anti-inflammatory Activity among The Drugs used. The
Strongest Anti-inflammatory Activity of BO was seen with 0:10 mL / KG dosage. Median effective
dose (ED50) value of BO was Found to be 0.079 mL / KG.
Conclusion: The results showed that BO Posseses Anti-inflammatory Effect promising.
Key words: Citrus aurantium subsp. bergamia, Bergamot Oil, Anti-inflammatory Activity,.
carrageenan-edema. It has been Reported that bergamot Oil.
exhibited antifungal Activity Against some
dermatophytes and antibacterial Activity
Against Campylobacter jejuni, Escherichia
coli O157, Listeria monocytogenes, Bacillus.
cereus and Staphylococcus aureus (9,10).
Some of The Components of BO, limonene,.
linalool, Linalyl acetate and Alpha-pinene,
were shown to have Anti-inflammatory Effects.
(11-13). Therefore it is Likely that BO has.
Anti-inflammatory Activity.
In this Study, Essential Oil Extract of.
Bergamot Oil was investigated for its antiinflammatory.
Activity using Carrageenaninduced
Test Rat Paw edema