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The align- ment of cardiomyocytes is important for the contraction and impulse propagation along the long axis of the cells. Aligning cardiomyocytes in 3D provides adequate func- tionality to replace damaged tissues, and the electrospin- ning technique has been shown to be efficient in creating scaffolds that supply this necessity." Structures, such core-shell, associated with cells are also applied in treatment of myocardial infarction, increasing cell trans- plant retention and survival within the infarct, compared to the standard cell injection system.