4.2 When the action potential reaches the presynaptic terminal will cause depolarization (by action potential to make the presynaptic terminal Ca ++ -channel opening) and Ca ++, many will flow to the area. It is believed that the Ca ++ protein to bind to the inner surface of the synaptic membrane of the terminal area of the neurotransmitter. Will be released (release site) makes vesicle containing neurotransmitter. Island connected to the membrane and fuse as homogeneous, it is open to the outside (exocytosis) neurotransmitter. Will be released at the synaptic cleft.
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