The result of the research shows that 30% of ethyl alcohol is entered, size 3.76 Ku/kg. Once a day for a period of 28 days to a large white rat, and long enough to be induced liver cell destruction a chronic Demi. Detected by cell swelling. Blood vessels grow abnormally wide. Neutrophil white blood cells were found, with a lot of fatty change and found the death of cells (cell necrosis) in conjunction with the. The poison of alcohol was found to cause liver cell damage occurring. Around the central vein is expected due to cytochrome P450 enzyme is the area most CYP2E1 when ethanol very lopriman is the stimulation increases. Metabolism of alcohol through this system will provide different output in conjunction with. Especially the free saronumun groups and hydrogen peroxide (hydrogen peroxide), while around the central vein with antioxidant broilers and little oxygen, which is harmful to the cell increases. The destruction of liver cells, in effect making the liver enzyme ALT and AST from out of the liver and the blood are higher in quantity.
การแปล กรุณารอสักครู่..