Six iridoids, geleganoids, designated A–F, and five iridoid glycosides, geleganosides A and B together with
three previously reported compounds, were isolated from leaves of Gelsemium elegans. Their structures
were elucidated by spectroscopic and chemical analyses. The relative configuration of geleganoid A
was confirmed by X-ray crystallographic diffraction analysis, and the absolute configuration of geleganoid
B was determined by a modified Mosher’s method. Selected compounds were evaluated for PC12
cell neurite outgrowth activity, but they were inactive
Six iridoids, geleganoids, designated A–F, and five iridoid glycosides, geleganosides A and B together withthree previously reported compounds, were isolated from leaves of Gelsemium elegans. Their structureswere elucidated by spectroscopic and chemical analyses. The relative configuration of geleganoid Awas confirmed by X-ray crystallographic diffraction analysis, and the absolute configuration of geleganoidB was determined by a modified Mosher’s method. Selected compounds were evaluated for PC12cell neurite outgrowth activity, but they were inactive
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Six iridoids, Geleganoids, Designated A-F, and fi Ve iridoid glycosides, Geleganosides A and B Together with
previously Reported Three compounds, were isolated from leaves of Gelsemium elegans. Their Structures
were elucidated by spectroscopic and Chemical analyzes. The relative con fi Guration of Geleganoid A
was con fi by X-ray crystallographic Rmed diffraction analysis, and The Absolute con fi Geleganoid Guration of
a modi fi ed B was Determined by Mosher's Method. Selected compounds were evaluated for PC12
Cell Neurite outgrowth Activity, but they were inactive.
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Six iridoids geleganoids designated A,, -, F and fi ve iridoid glycosides geleganosides A, and B together with
three previously. Reported compounds were isolated, from leaves of Gelsemium elegans. Their structures
were elucidated by spectroscopic and. Chemical analyses. The relative con fi guration of geleganoid A
was con fi rmed by X-ray crystallographic, diffraction analysisAnd the absolute con fi guration of geleganoid
B was determined by a modi fi ed Mosher 's method. Selected compounds were evaluated. For PC12
cell neurite, outgrowth activity but they were inactive
.
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