Translocations at chromosomal band

Translocations at chromosomal band Hq23 characterize most de novo
acute lymphoblastic leukemia* (ALL) of infants, acute myeloid leukemias
(AMD of infants and young children, and secondary AMLs following
epipodophyllotoxin exposure. The chromosomal breakpoints at Ilq23
have been cloned from isolated cases off/c novo ALL and AMI . Using an
859-base pair /¡«millfragment of human ALL-1 complementary DNA
that recognizes the genomic breakpoint region for de novo ALL and AML, we investigated two cases of secondary AML that followed etoposidetreated
primary B-lineage ALL. In the first case, the translocation oc
curred between chromosomes 9 and 11 and the breakpoint at Hq23 lo
calized to the same 9-kilobase region of the ALL-1 gene that is disrupted
in most of the de novo leukemias. In the second case the translocation was between chromosomes 11 and 19. The breakpoint occurred outside of the
ALL-1 breakpoint cluster region.

ผลลัพธ์ (อังกฤษ) 1:

Translocations at chromosomal band Hq23 characterize most de novoacute lymphoblastic leukemia* (ALL) of infants, acute myeloid leukemias(AMD of infants and young children, and secondary AMLs followingepipodophyllotoxin exposure. The chromosomal breakpoints at Ilq23have been cloned from isolated cases off/c novo ALL and AMI . Using an859-base pair /¡«millfragment of human ALL-1 complementary DNAthat recognizes the genomic breakpoint region for de novo ALL and AML, we investigated two cases of secondary AML that followed etoposidetreatedprimary B-lineage ALL. In the first case, the translocation occurred between chromosomes 9 and 11 and the breakpoint at Hq23 localized to the same 9-kilobase region of the ALL-1 gene that is disruptedin most of the de novo leukemias. In the second case the translocation was between chromosomes 11 and 19. The breakpoint occurred outside of theALL-1 breakpoint cluster region.

ผลลัพธ์ (อังกฤษ) 2:

Translocations at chromosomal Band Hq23 characterize Most de novo
acute lymphoblastic leukemia * (ALL) of Infants, acute myeloid leukemias
(AMD of Infants and Young children, and Secondary AMLs following
Epipodophyllotoxin exposure. The chromosomal breakpoints at Ilq23
have been cloned from isolated Cases off /. C ALL novo and AMI. Using an
859-Base pair / hissy «Human Millfragment of ALL-1 Complementary DNA
Recognizes that the de novo genomic breakpoint Region for ALL and AML, we investigated Two Cases of Secondary AML that followed Etoposidetreated
primary B. -lineage ALL. in the First Case, the OC translocation
between chromosomes 9 and 11 and the Curred breakpoint at Hq23 Lo
Calized to the Same-Kilobase Region 9 of the ALL-1 Gene that is disrupted
in de novo Most of the leukemias. in. the second was translocation between chromosomes 11 and the Case 19. The breakpoint occurred Outside of the
ALL-1 breakpoint Cluster Region.

ผลลัพธ์ (อังกฤษ) 3:

Translocations at chromosomal band Hq23 characterize most de novo.Acute lymphoblastic leukemia * (ALL), of infants acute myeloid leukemias.(AMD of infants and, young children and secondary AMLs following.Epipodophyllotoxin exposure. The chromosomal breakpoints at Ilq23.Have been cloned from isolated cases off / C novo ALL and AMI. Using an.859 - base pair /  in a  millfragment of human ALL-1 complementary DNA.That recognizes the genomic breakpoint region for de novo ALL and AML we investigated, two cases of secondary AML that. Followed etoposidetreated.Primary B-lineage ALL. In the, first case the translocation OC.Curred between chromosomes 9 and 11 and the breakpoint at Hq23 lo.Calized to the same 9-kilobase region of the ALL-1 gene that is disrupted.In most of the de novo leukemias. In the second case the translocation was between chromosomes 11 and 19. The breakpoint. Occurred outside of the.ALL-1 breakpoint cluster region.