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Minerals prevent the oxidation of lipids in the, cell membraneWhich can reduce oxidative stress affecting immune cells. For.Instance selenium is, indispensable to the function of reducing.Enzymes such as glutathione peroxidase and thioredoxin.Reductase and is, needed to stimulate cell-mediated immune.Functions (156). Furthermore zinc may, be required for the.Translocation and binding of NF-B to DNA (157).Long-chain PUFAs in foods can modulate immune functions.Dietary n-3 PUFAs alter the lipid composition of the cell.Membrane and regulate the function of immune cells. Antigenpresenting.Cells from mice and humans fed n-3 PUFAs.Exhibited the capacity to suppress excessive activation of.T, cells (158 159). As, a result n-3 PUFAs can act as antiinflammatory.Agents.Major food-derived substances and their immune-modulating.Functions are summarized in Table 2.