In the advanced stages of Parkinson

In the advanced stages of Parkinson's disease, patients may begin to experience "off" time, or periods of poor mobility, slowness and stiffness. Additionally, in Parkinson's disease patients, the spontaneous emptying of the stomach becomes delayed and unpredictable, which can affect the timing of when orally administered medicines leave the stomach and are absorbed in the small intestine. DUOPA provides patients with the same active ingredients as orally-administered carbidopa and levodopa immediate release, but is delivered in a suspension that goes directly into the small intestine via a tube placed by a percutaneous endoscopic gastrostomy procedure with jejunal extension (PEG-J). This type of administration is intended to bypass the stomach.

ผลลัพธ์ (แอฟริกา) 1:

In die gevorderde stadiums van Parkinson se siekte, kan pasiënte begin om "af" tyd, of tydperke van swak mobiliteit, traagheid en styfheid ervaar. Verder, in siekte Parkinson se pasiënte, die spontane leegmaak van die maag raak vertraag en onvoorspelbaar, wat die tydsberekening van wanneer mondelings toegedien medisyne laat die maag en is opgeneem in die dunderm kan beïnvloed. DUOPA bied pasiënte met dieselfde aktiewe bestanddele as mondelings geadministreer karbidopa en levodopa onmiddellike vrylating, maar word gelewer in 'n skorsing wat direk via 'n buis geplaas deur 'n perkutane endoskopiese prosedure gastrostomie met jejunal uitbreiding (PEG-J) gaan in die dunderm. Hierdie tipe van die administrasie is bedoel om die maag omseil.