The benzoic acid derivative was also tested against clinical
isolates (susceptible and resistant) (Table 4). The MICs for the
clinical isolates ranged from 125 mg/mL to >250 mg/mL. The
biological effect of the benzoic acid derivative has been previously
reported, but not against M. tuberculosis. Terreaux et al. (1998)
isolated four benzoic acid derivatives from leaves of P. dilatatum,
which displayed antifungal activity against Cladosporium cucumerinum
by a bioautographic test, with MICs from 1 to 5 mg/mL.