Following osteoclast-mediated bone resorption through the secretion of tartrate-resistant acid phosphatase (TRAP) and cathepsin K, osteoblast-mediated bone formation begins initiated by the release of osteoprotegerin (OPG) from osteoblasts to inhibit osteoclastogenesis through OPG-RANKL binding; the OPG/RANKL ratio is a critical transition point for bone cell activity.
การแปล กรุณารอสักครู่..
