Frequent consumption of nuts has been linked to a lowered risk of cardiovascular disease. Phytochemicals especially phenolics,,, In nuts may be considered to be the major bioactive compounds for health benefits. Nine types of tree nuts and peanuts commonly. Available in the United States were evaluated for total phenolic and flavonoid contents antioxidant and antiproliferative,,, Activities.The profiles of total phenolics, and flavonoids including both soluble free and bound forms were investigated, by utilizing. Solvent extraction base, solid-phase, digestion and extraction methods. Walnuts had the highest total phenolic and flavonoid. Contents (1580.5). "58.0 convert mg / 100), as G 744.8 edge." 93.3 mg / 100), g respectively). Walnuts also possessed the highest total antioxidant. Activity (458.1 "edge" 14.0 as thermal mol of vitamin C equiv / g of nut). Both soluble phenolic and flavonoid contents were positively correlated with total. Antioxidant activity (R2 "=", "<" 0.9901 P 0.05; and R2 "=", "0.9749 P <), 0.05 respectively). The proliferation of HepG2 and Caco-2. Cells was significantly inhibited in a dose-dependent pattern after exposure to the extracts, of nutsWith walnuts and pecans exhibiting the highest antiproliferative activity. These results provide new knowledge about health. Functions of nuts and may influence consumers toward purchasing nuts exhibiting greater potential health benefits.
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