We also conducted several post hoc

We also conducted several post hoc analyses (Figure 3FIGURE 3
Relative Hazard of the Termination of Pregnancy before 37 Weeks, According to Subgroup.
). Because it is possible that treatment may improve the outcomes of pregnancy only in women with more severe disease, we performed analyses that were limited to women with extensive gingival bleeding (the highest one third or two thirds of patients in terms of the percentage of bleeding on probing at baseline) or periodontal pocketing (the highest third of patients in terms of the percentage of sites with a probing depth ≥4 mm). In these subgroups, the risk of preterm delivery did not differ significantly between the treatment and control groups (Figure 3). Although preterm births were more frequent in our study than in earlier trials of periodontal treatment,14,15 we also performed analyses that were limited to women with previous preterm births or with a previous preterm birth, spontaneous or induced abortion, or stillbirth, and found similar results (Figure 3).
Noncompliance with study treatment may have diluted a treatment effect. Yet we found no significant effect of periodontal treatment on the risk of preterm delivery at the two sites (Minnesota and Kentucky) with the highest compliance and the largest periodontal treatment effects or among the subgroup of patients who had four or more follow-up visits (Figure 3).
Another possibility is that the periodontal treatment did not affect periodontitis sufficiently to affect birth outcomes. However, we also found no significant effects of treatment on preterm births in analyses comparing all patients in the control group with only the “best responders” to treatment, as defined by the highest third of proportional reduction in the percentage of bleeding on probing (i.e., a reduction of at least 40%; P=0.59) (Figure 3); the lowest residual percentage of bleeding on probing after treatment (35.7% or less, P=0.26); or periodontal condition after treatment that did not meet the eligibility criteria of the study, which occurred among 178 women in the treatment group (P=0.48).

ผลลัพธ์ (อังกฤษ) 2:

Post hoc analyzes we also conducted several (Figure 3 3FIGURE
Relative Hazard of the Termination of Pregnancy before 37 Weeks, According to Subgroup.
). Because it is possible that treatment may improve the outcomes of pregnancy only in women with more severe disease, we performed analyses that were limited to women with extensive gingival bleeding (the highest one third or two thirds of patients in terms of the percentage of bleeding on. probing at baseline) or periodontal pocketing (the highest third of patients in terms of the percentage of sites with a probing depth ≥4 mm). In these subgroups, the risk of preterm delivery did not differ significantly between the treatment and control groups (Figure 3). Although preterm births were more frequent in our study than in earlier trials of periodontal treatment, 14,15 we also performed analyses that were limited to women with previous preterm births or with a previous preterm birth, spontaneous or induced abortion, or stillbirth, and found. similar results (Figure 3).
noncompliance with Treatment Study May have diluted a Treatment Effect. Yet we found no significant effect of periodontal treatment on the risk of preterm delivery at the two sites (Minnesota and Kentucky) with the highest compliance and the largest periodontal treatment effects or among the subgroup of patients who had four or more follow-up visits (. figure 3).
Another possibility is that the periodontal Treatment did not affect periodontitis Sufficiently to affect birth outcomes. However, we also found no significant effects of treatment on preterm births in analyses comparing all patients in the control group with only the "best responders" to treatment, as defined by the highest third of proportional reduction in the percentage of bleeding on probing (ie. , a reduction of at least 40%; P = 0.59) (Figure 3); the lowest residual percentage of bleeding on probing after treatment (35.7% or less, P = 0.26); or periodontal condition after treatment that did not meet the eligibility criteria of the study, which occurred among 178 women in the treatment group (P = 0.48).