Degeneration of cells in the SNc, which is responsible for producing dopamine as a result, the amount of dopamine in the brain are less. Normally, dopamine has been changed from the amino acid tyrosine by the enzyme Tyrosine hydroxylase using the name (TH)) it is TH. much less in patients with Parkinson's disease. After dopamine was produced, it will be changed later by the enzyme Monoamine oxidase a (MAO) is called and the Catechol-O-methyl transferase (COMT) until a final document called nillic acid Homova (HVA) before it is removed from the body enzymes COMT and MAO, this is important because it is the position of the medications used to treat Parkinson's disease. In the present. Effect by inhibition of the enzymes mentioned.
การแปล กรุณารอสักครู่..