Two new lignans, magnovatins A (1)

Two new lignans, magnovatins A (1) and B ( 2), along with nine known compounds, were isolated from the leaves of Magnolia oVata. The known compounds were identified as acuminatin (3), licarin A (4), kadsurenin M, 4-O- demethylkadsurenin M, oleiferin A, oleiferin C, spathulenol, parthenolide, and 11,13-dehydrocompressanolide. In addition, compounds 1 and 2 yielded four new derivatives (1a, 1b, 2a, and 2b). The structures of the new compounds were established on the basis of spectrometric data evaluation. Free-radical scavenging and antimicrobial activities of the major compunds 1, 3, and 4 were investigated.

Two new lignans, magnovatins A (1) and B (2), along with nine known compounds, were isolated from the leaves of Magnolia oVata. The known compounds were identi fi ed as acuminatin (3), licarin A (4), kadsurenin M, 4-O- demethylkadsurenin M, oleiferin A, oleiferin C, spathulenol, parthenolide, and 11,13-dehydrocompressanolide. In addition, compounds 1 and 2 yielded four new derivatives (1a, 1b, 2a, and 2b). The structures of the new compounds were established on the basis of spectrometric data evaluation. Free-radical scavenging and antimicrobial activities of the major compunds 1, 3, and 4 were investigated.

Two, new lignans magnovatins A (1) and B (2), along with nine known compounds were isolated, from the leaves of Magnolia. OVata. The known compounds were identi fi ed as acuminatin (3), licarin A (4), kadsurenin M 4-O - demethylkadsurenin M oleiferin,,, A oleiferin C spathulenol,,,,, parthenolide and 11 13-dehydrocompressanolide. In addition compounds 1, and 2 yielded four. New derivatives (1a 1b 2a,,,And 2b). The structures of the new compounds were established on the basis of spectrometric data evaluation. Free-radical. Scavenging and antimicrobial activities of the major, compunds 1 3 and 4, were investigated.
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