A new antifungal compound, Sch 3713

A new antifungal compound, Sch 37137, was isolated from the cultured broth of a Micromonospora sp., SCC 1792. Sch 37137 is structurally related to A 19009, a dipeptide previously discovered from a Streptomyces sp. The compound was weakly active against species of Candida and dermatophytes (mean MICs greater than or equal to 128 micrograms/ml) in Sabouraud dextrose, yeast-nitrogen and modified Eagles minimum essential media; however activity against Candida sp. (mean MICs greater than or equal to 12 micrograms/ml) and dermatophytes (mean MICs greater than or equal to 0.8 microgram/ml) significantly improved in MA medium.

ผลลัพธ์ (อังกฤษ) 1:

A new antifungal compound, Sch 37137, was isolated from the cultured broth of a Micromonospora sp., SCC 1792. Sch 37137 is structurally related to A 19009, a dipeptide previously discovered from a Streptomyces sp. The compound was weakly active against species of Candida and dermatophytes (mean MICs greater than or equal to 128 micrograms/ml) in Sabouraud dextrose,A new antifungal compound, Sch 37137, was isolated from the cultured broth of a Micromonospora sp., SCC 1792. Sch 37137 is structurally related to A 19009, a dipeptide previously discovered from a Streptomyces sp. The compound was weakly active against species of Candida and dermatophytes (mean MICs greater than or equal to 128 micrograms/ml) in Sabouraud dextrose,

ผลลัพธ์ (อังกฤษ) 3:

A new compound antifungal, 37137 Sch, isolated was from the cultured broth of a Micromonospora SP, SCC 1792. Sch 37137 is. Structurally related to, A 19009 a dipeptide previously discovered from a Streptomyces sp. The compound was weakly active. Against species of Candida and dermatophytes (mean MICs greater than or equal to 128 micrograms / ml), in Sabouraud dextroseA new compound antifungal, 37137 Sch, isolated was from the cultured broth of a Micromonospora SP, SCC 1792. Sch 37137 is. Structurally related to, A 19009 a dipeptide previously discovered from a Streptomyces sp. The compound was weakly active. Against species of Candida and dermatophytes (mean MICs greater than or equal to 128 micrograms / ml), in Sabouraud dextroseYeast-nitrogen and modified Eagles minimum essential media; however activity against Candida sp. (mean MICs greater than. Or equal to 12 micrograms / ml) and dermatophytes (mean MICs greater than or equal to 0.8 microgram / ml) significantly improved. In MA medium.